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CASPASE 10
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DeCS
Descriptor
English
:
Caspase 10
Descriptor
Spanish
:
Caspasa 10
Descriptor
Portuguese
:
Caspase 10
Synonyms
English
:
Caspase 10 a
Caspase 10 c
Caspase 10 d
Caspase 10-a
Caspase 10-c
Caspase 10-d
Caspase 10a
Caspase 10c
Caspase 10d
Caspase-10
Mch4 Protease
Protease, Mch4
Tree Number:
D08.811.277.656.262.500.126.550.910
D08.811.277.656.300.200.126.550.910
D12.644.360.075.405.550.910
D12.776.476.075.405.550.910
Definition
English
:
A long pro-domain caspase that contains a
death effector domain
in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal
death effector domain
with
DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS
.
Caspase 10
plays a role in
APOPTOSIS
by cleaving and activating
EFFECTOR CASPASES
. Several isoforms of this protein exist due to multiple
alternative splicing
of its MESSENGER RNA.
Entry Combination - descr/qualif
English
:
Caspase 10
/
antagonists & inhibitors
use
Caspase Inhibitors
See Related
English
:
Autoimmune Lymphoproliferative Syndrome
History Note
English
:
2007(1998)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52229
Unique Identifier:
D053455
Occurrence in VHL
:
Similar:
DeCS